What does PT-141 (bremelanotide) cost in each channel?
Prices in US dollars at the verification date. Ranges are published list or program prices where a primary source exists; notes say when a figure is a typical market range instead.
| Channel | Price (USD) | Notes |
|---|---|---|
| With insurance | $0 to $25per dose | Out of pocket per autoinjector through the manufacturer savings program, checked 2026-09-22 on the manufacturer's patient site: most commercially insured patients pay $0 for a four-dose box, and patients whose insurance does not cover Vyleesi, or who have no insurance, can buy a four-dose box for $99 ($24.75 per dose). Coverage applies to the approved indication (acquired, generalized hypoactive sexual desire disorder in premenopausal women). [1] [2] |
| Branded, from a pharmacy | $233 to $239per dose | Vyleesi retail cash price per 1.75 mg autoinjector. A published cash price listing checked 2026-09-22 showed $930.00 to $956.15 for one carton of four autoinjectors, which is the size of each prescription. Cash prices do not apply to insurance claims. [3] [5] |
| Telehealth program | $187 to $224per month | A licensed telehealth provider's published price for compounded bremelanotide nasal spray, checked 2026-09-22: $224 per month on a 3 month plan, $204 on a 6 month plan, and $187 on a 12 month plan, prescribed after a physician consultation and compounded by an FDA registered pharmacy. Compounded nasal and vial forms are not FDA approved formulations and are commonly prescribed off-label, including to men. [4] [6] |
| Compounded pharmacy | Not published | No dated lawful 503A pharmacy price found. The one published per-vial pharmacy list we had checked also marketed routine compounded GLP-1 copies and research-style stacks, so we do not use it as a source. Compounded prices are usually bundled into the telehealth or clinic channels above. [6] |
What is the list price of PT-141 (bremelanotide)?
The manufacturer does not publish a list price on its prescriber site. Retail cash prices checked 2026-09-22 ran about $930 to $956 per four-autoinjector carton, while the manufacturer savings program brings most patients to $0 with coverage or $99 without it.
Does insurance cover PT-141 (bremelanotide)?
Commercial coverage for Vyleesi varies and often requires prior authorization for the approved HSDD indication in premenopausal women. Use in men and compounded products are not covered.
What changes the price?
- Branded autoinjector versus compounded vial or spray
- Eligibility for the manufacturer savings program
- Number of doses used per month (as-needed dosing)
- Telehealth plan length and visit fees
Frequently asked questions
How much does PT-141 (bremelanotide) cost without insurance?
About $187 to $224 per month at the verification date, depending on the channel: telehealth program. See the table above for what each figure includes. [4] [6]
Does insurance cover PT-141 (bremelanotide)?
Commercial coverage for Vyleesi varies and often requires prior authorization for the approved HSDD indication in premenopausal women. Use in men and compounded products are not covered. [1] [2]
What is the list price of PT-141 (bremelanotide)?
The manufacturer does not publish a list price on its prescriber site. Retail cash prices checked 2026-09-22 ran about $930 to $956 per four-autoinjector carton, while the manufacturer savings program brings most patients to $0 with coverage or $99 without it. [3] [5]
Related pages
From the blog
- Peptides for women, ranked by human evidence
GLP-1 drugs, teriparatide, abaloparatide, and Vyleesi (PT-141) have real trials in women. Kisspeptin is research-only and GHK-Cu rests on small skin studies. The ranking and legal status.
Sources
- [1]Vyleesi (bremelanotide) prescriber site: coding, coverage, and patient savings program
- [2]Vyleesi (bremelanotide) manufacturer patient site, savings program terms, accessed 2026-09-22
- [3]Published retail cash price listing for bremelanotide autoinjectors, accessed 2026-09-22
- [4]Licensed telehealth provider price page for compounded bremelanotide nasal spray, accessed 2026-09-22
- [5]FDA prescribing information for Vyleesi (bremelanotide injection), via DailyMedFDA
- [6]FDA: Compounding and the FDA, questions and answersFDA