IMMUNE / INFLAMMATION / PEPTIDE CARD

LL-37

A human antimicrobial peptide involved in innate immune signaling and host defense.

PEPTIDE CARDLL-37
Reviewed
August 8, 2026
Human evidence
1/5 · No established therapeutic program
U.S. FDANot FDA approved
2026 WADANot specifically named
Inspect 3 sources
On this page

WHAT THE EVIDENCE SAYS

LL-37 evidence summary.

LL-37 is an important endogenous host-defense peptide, but complex pro-inflammatory, anti-inflammatory, antimicrobial, and cytotoxic actions make simple immune-support claims misleading.

Entity type
Native peptide
Source snapshot
August 8, 2026
Record status
Sources attached
Do not overread this record

Describing an endogenous function does not establish that administering a manufactured product is safe or beneficial.

01 / CLASSIFICATION

What is LL-37?

Entity typeNative peptide
Research categoryImmune / Inflammation
Known namesLL-37
Editorial unitOne molecule or defined product record

Names, fragments, salts, formulations, routes, and branded products are kept distinct whenever transferring evidence would change the conclusion.

02 / EVIDENCE

LL-37 human and preclinical evidence.

HUMAN
1/5 · No established therapeutic program

The human peptide is well characterized biologically, but a reliable clinical efficacy program for marketed LL-37 products was not identified.

PRECLINICAL
4/5 · Extensive innate-immune research

Antimicrobial, inflammatory, and cytotoxic effects are extensively studied in laboratory systems.

The five-point bars describe the maturity and depth of the evidence base. They do not score effectiveness, safety, or personal suitability.

03 / STATUS

LL-37 FDA and sport status.

U.S. FDANo FDA-approved LL-37 drug product; FDA reports insufficient human safety information for compounded LL-37 products.
2026 WADANot specifically named in the 2026 WADA List; athletes should verify current status and product contents.
Commercial accessPeptideAgent does not route unapproved research substances to sellers.

Status summaries are educational and time-sensitive. Consult current official labeling and anti-doping resources for a decision.

04 / RESEARCH AREAS

What is LL-37 being studied for?

01Antimicrobial defense
02Innate immunity
03Inflammation
04Cytotoxicity

05 / COMPARISONS

Compare LL-37.

06 / LATEST & DEFINING SOURCES

LL-37 primary and official sources.

07 / QUESTIONS

Questions about LL-37.

Start with identity, research, human evidence, approval, sport status, and the limits of the current record.