What does MOTS-c cost in each channel?
Prices in US dollars at the verification date. Ranges are published list or program prices where a primary source exists; notes say when a figure is a typical market range instead.
| Channel | Price (USD) | Notes |
|---|---|---|
| With insurance | Not published | Not covered. Medicare Part D and commercial pharmacy benefits cover FDA approved drugs for accepted indications; compounded or unapproved peptides are paid in cash. [4] |
| Compounded pharmacy | Not published | No lawful compounded price. MOTS-c was withdrawn from 503A Category 2 in April 2026 and recommended for the 503A bulks list by PCAC in July 2026, but the recommendation is advisory: until FDA publishes a final rule it is not on the bulks list, and a 503A pharmacy has no federal basis to compound it from bulk. Advertised clinic prices are not a comparable price, and products sold as research chemicals are not lawful for human use. [1] [2] [3] |
What is the list price of MOTS-c?
There is no list price: MOTS-c is not an FDA approved drug. Research chemical listings are not lawful for human use and are not a comparable price.
Does insurance cover MOTS-c?
Not covered by commercial plans or Medicare because it is an unapproved compounded product.
What changes the price?
- No lawful compounding basis until FDA adds the substance to the 503A bulks list by final rule
Frequently asked questions
How much does MOTS-c cost without insurance?
No lawful compounded price. MOTS-c was withdrawn from 503A Category 2 in April 2026 and recommended for the 503A bulks list by PCAC in July 2026, but the recommendation is advisory: until FDA publishes a final rule it is not on the bulks list, and a 503A pharmacy has no federal basis to compound it from bulk. Advertised clinic prices are not a comparable price, and products sold as research chemicals are not lawful for human use. [1] [2] [3]
Does insurance cover MOTS-c?
Not covered by commercial plans or Medicare because it is an unapproved compounded product. [4]
What is the list price of MOTS-c?
There is no list price: MOTS-c is not an FDA approved drug. Research chemical listings are not lawful for human use and are not a comparable price.
Related pages
- MOTS-c: evidence, legality, and access
- Epitalon vs MOTS-c (Epitalon cost)
- MOTS-c vs humanin
- MOTS-c vs SS-31 (elamipretide) (SS-31 (elamipretide) cost)
- NAD+ vs MOTS-c (NAD+ cost)
- Longevity and healthy aging: peptide evidence
- Insulin resistance and prediabetes: peptide evidence
- Mitochondrial disease and dysfunction: peptide evidence
- Where it is legal to get: peptide law by state
- Full cost index
From the blog
- MOTS-c for weight loss: what mouse and human studies show
MOTS-c prevented diet-induced obesity in mice, but no human trial has tested it for weight loss. What the mouse data show, what human blood studies found, and where it stands legally.
Sources
- [1]FDA: July 23-24, 2026 meeting of the Pharmacy Compounding Advisory Committee (BPC-157, KPV, TB-500, MOTS-c, DSIP, semax, epitalon)FDA
- [2]FDA: Bulk drug substances used in compounding under section 503A of the FD&C Act (links to the Category 1, 2, and 3 lists and the bulks list)FDA
- [3]FDA: Certain bulk drug substances for use in compounding may present significant safety risks (Category 2 list and withdrawn nominations, content current as of April 22, 2026)FDA
- [4]Medicare.gov: prescription drug coverage (Part D and outpatient drugs)