ENTITY CLASS
Incretin receptor agonists
Approved and investigational GLP-1, GIP, and glucagon receptor agonists used or studied in metabolic medicine.
CONNECTED RECORDS
Incretin receptor agonists: evidence by entity.
Peptide analogHuman evidence 5/5
Semaglutide
Semaglutide has a mature evidence base, but claims must remain tied to the specific product, indication, population, and label.
Open evidence recordPeptide analogHuman evidence 5/5
Tirzepatide
Tirzepatide is an approved dual-receptor medicine with a mature human evidence base; it is not interchangeable with investigational retatrutide.
Open evidence recordPeptide analogHuman evidence 4/5
Retatrutide
Retatrutide has meaningful randomized human evidence, but it should not be described as an available approved alternative to semaglutide or tirzepatide.
Open evidence record