OTHER / PEPTIDE CARD

Melanotan II

An unapproved synthetic melanocortin analog promoted for tanning and sexual effects despite important safety uncertainty.

PEPTIDE CARDMelanotan II

Reviewed
August 8, 2026

Human evidence

1/5 · Case reports, not efficacy trials

U.S. FDANot FDA approved

2026 WADANot specifically named

Inspect 3 sources

On this page

WHAT THE EVIDENCE SAYS

Melanotan II evidence summary.

Melanotan II has no approved tanning or sexual-health use, and the available human record provides more reason for safety concern than confidence in benefit.

Entity type
Melanocortin receptor agonistSource snapshot
August 8, 2026Record status
Sources attached

Do not overread this record

Visible pigmentation is a biological effect, not evidence that an unapproved product is safe, pure, or medically appropriate.

01 / CLASSIFICATION

What is Melanotan II?

Entity typeMelanocortin receptor agonist

Research categoryOther

Known namesMelanotan II

Editorial unitOne molecule or defined product record

Names, fragments, salts, formulations, routes, and branded products are kept distinct whenever transferring evidence would change the conclusion.

Class: Melanocortin agonists Goal: Sexual Health & Melanocortins

02 / EVIDENCE

Melanotan II human and preclinical evidence.

HUMAN

1/5 · Case reports, not efficacy trials

Published human evidence is dominated by adverse-event reports and uncontrolled use rather than a reliable therapeutic program.

PRECLINICAL

2/5 · Melanocortin activity

Receptor activity and pigmentation biology do not establish a safe tanning or sexual-health product.

The five-point bars describe the maturity and depth of the evidence base. They do not score effectiveness, safety, or personal suitability.

03 / STATUS

Melanotan II FDA and sport status.

U.S. FDANo FDA-approved Melanotan II drug product; FDA identifies safety and immunogenicity concerns and has warned about illegal marketing.

2026 WADANot specifically named in the 2026 WADA List; athletes should verify current status and product contents.

Commercial accessPeptideAgent does not route unapproved research substances to sellers.

Status summaries are educational and time-sensitive. Consult current official labeling and anti-doping resources for a decision.

04 / RESEARCH AREAS

What is Melanotan II being studied for?

01Melanocortin receptors

02Pigmentation

03Adverse-event surveillance

04Sexual effects

05 / COMPARISONS

Compare Melanotan II.

PT-141 vs Melanotan IIAn FDA-reviewed bremelanotide product compared with an unapproved melanocortin analog.

06 / LATEST & DEFINING SOURCES

Melanotan II primary and official sources.

Case report / 2020Renal infarction associated with Melanotan II use

PubMed

FDA / 2026Bulk substances that may present significant safety risks

U.S. FDA

FDA / 2007FDA report on illegally marketed Melanotan products

U.S. FDA

07 / QUESTIONS

Questions about Melanotan II.

Start with identity, research, human evidence, approval, sport status, and the limits of the current record.

EvidenceWhat is the evidence for Melanotan II?

Melanotan II has no approved tanning or sexual-health use, and the available human record provides more reason for safety concern than confidence in benefit.

ResearchWhat is Melanotan II being studied for?

Current source-backed research areas include Melanocortin receptors, Pigmentation, Adverse-event surveillance, Sexual effects. These areas describe investigation, not established personal benefit.

FDA statusIs Melanotan II FDA approved?

Current U.S. status for Melanotan II: No FDA-approved Melanotan II drug product; FDA identifies safety and immunogenicity concerns and has warned about illegal marketing.

Sport statusIs Melanotan II prohibited in sport?

Current sport-status snapshot for Melanotan II: Not specifically named in the 2026 WADA List; athletes should verify current status and product contents.

Evidence limitsWhat are the main evidence limits for Melanotan II?

Visible pigmentation is a biological effect, not evidence that an unapproved product is safe, pure, or medically appropriate.